Cocoliztli epidemic: 1545-1548

The disease that caused the cocoliztli pandemic was a type of viral hemorrhagic fever that murdered 15 million occupants of Mexico and Central America. Among a populace previously debilitated by outrageous dry season, the malady end up being absolutely cataclysmic. "Cocoliztli" is the Aztec word for "bug."

An ongoing report that inspected DNA from the skeletons of casualties found that they were tainted with a subspecies of Salmonella known as S. paratyphi C, which causes enteric fever, a class of fever that incorporates typhoid. Enteric fever can cause high fever, lack of hydration and gastrointestinal issues is as yet a significant wellbeing risk today.